Printed electronics using polymer thick film (PTF) is experiencing commercial growth when printed onto soft, pliable or stretchable substrate. PTF electronics on traditional polyester (PET) film has reached higher levels of durability with recent design and material advancements, but is limited at 2-D flexing, is not pliable, and can be a noisy or noticeable interface. The material durability advancements on PET film have proven to work on pliable substrates. The advantage of pliable electronics over PET film-based electronics is a circuit that can be flexed in 3-D for a soft and quiet human-machine or bio-sensor interface. This presentation will describe several ink-substrate combinations for incorporating PTF circuitry onto fabrics, prevailing performance levels, pertinent test methods being developed and commercial applications.